Anatomically?
Yeah, that's a pretty cool idea. I think its a good idea to know where you're hitting.
I took an anatomy class in high school and college, so I already know where to aim.
For the head, full on, try and hit the triangle between the eyes and the mouth. If from behind or the side, try and hit behind the ear or at the base of the neck. If in the chest, of course try and hit heart and lung, and of course, if they have good armor on, you can always take out their hips, and they'll drop like a rock if you break that.
I also study anatomy diagrams of animals as well, so I know where to hit them to take them down effectively, also, make sure they die cleanly.